Cheeseburger Casserole with Homemade Biscuit Topping Recipe
This easy Cheeseburger Casserole is a comforting, family-friendly meal made with ground beef, cheddar cheese, ketchup, and topped with biscuits. It’s a simple and delicious dinner that brings back childhood memories!
Some of the best recipes are the ones passed down through generations. My mom used to make this Cheeseburger Casserole when I was a little girl, and years later, it became a favorite for my boys, too. It’s one of those dishes that feels like a warm hug—simple ingredients, easy steps, and the kind of home-cooked goodness that brings everyone to the table.
With a base of browned ground beef, a layer of ketchup, and plenty of melted cheddar cheese, it’s finished off with a fluffy biscuit topping. I love making it with homemade biscuits, but for an even quicker version, store-bought biscuits work great, too!
Why You’ll Love this Easy Cheeseburger Casserole with Biscuit Topping
- Easy & Quick – Minimal prep with simple pantry staples.
- Family-Friendly – A kid-approved meal everyone enjoys.
- Comforting & Nostalgic – Just like mom used to make!
- Customizable – Use homemade biscuits or store-bought for convenience.
How to Portion, Cook, and Freeze This Recipe to Fit Your Lifestyle
- Making for Two: Cut the ingredients in half and bake in a smaller dish.
Freezing Ahead: Assemble the beef and cheese layers, then freeze. Add biscuits and bake fresh when ready.
Baking After Freezing: If baking from frozen, cover with foil and bake at a lower temp until heated through, then add biscuits and finish baking uncovered.
Rita Joy’s Favorite Kitchen Tools!
If I’m making this recipe for just the 2 of us, I use a small baking dish 6.5 x 10 inches (similar to this one) that is perfect for two. You can find lists of my favorites in my Amazon shop here on Amazon USA or Amazon Canada. (They are affilate links.)
Ingredients You’ll Need for this Cheeseburger Casserole Recipe:
Please refer to the printable recipe card at the bottom of this post for exact measurements.
For the Cheeseburger Base:
- Ground beef – A hearty and flavorful base for the casserole. I prefer to buy lean or extra lean ground beef.
- Ketchup – Adds a sweet and tangy layer of flavor. Our family favorite brand is Heinz!
- Cheddar cheese – Melts beautifully for a rich, cheesy topping.
For the Homemade Biscuits: (or use canned biscuits for a shortcut!) For more detailed instructions on this biscuit recipe, check out this post on Mom’s baking powder biscuits.
- Flour – The foundation for light, fluffy biscuits.
- Baking powder & baking soda – Essential leavening agents for a good rise.
- Sugar – A touch of sweetness balances the flavors.
- Salt – Enhances the biscuit flavor.
- Butter – Adds richness and flakiness.
- Milk – Helps bring the dough together for a tender texture.
Step by Step Instructions for Cheeseburger Casserole
Please refer to the printable recipe card at the bottom of this post for exact and detailed instructions.
1.Squirt ketchup right over the top of browned ground beef in a casserole dish. 2.Add a layer of shredded cheese. 3. Make biscuit dough. 5.Once baked to golden brown, slice and serve. 4.Lay biscuit dough on the top of the casserole.
Tips & Tricks for Making this Recipe
- Shortcut Tip: Use canned biscuits for an ultra-quick dinner!
- For Easy Biscuit Dough Rolling: I always get questions regarding what I roll the biscuit dough on. It is a pastry cloth and rolling pin cover (that I LOVE!). Click here to find the top tools and tips for rolling dough.
Substitutions & Variations
- Swap ketchup for BBQ sauce for a smoky flavor.
- Use ground turkey or chicken instead of ground beef for a leaner option.
- Add chopped onions or mushrooms for extra texture and taste.
- Mix a little Worcestershire sauce into the beef for depth.
- Add crispy bacon bits to the hamburger for a bacon cheeseburger casserole.
- Add in some corn or black beans to the hamburger mixture for some added goodness.
- Try mozzarella, Colby Jack, or a mix of cheeses for a different twist.
What to Serve with Cheeseburger Casserole
- A simple green salad with a tangy vinaigrette or poppy seed dressing.
- Steamed or roasted vegetables for a balanced meal.
- A side of pickles or coleslaw for a fresh crunch.
Other Weeknight Dinner Ideas
- This meatloaf recipe is the perfect comfort food meal
- Need to use up leftover turkey? This turkey casserole recipe is so quick & yummy – and you can substitute cooked chicken for the turkey if you’d like.
- Turn your soups & stews into a one pot dinner with this amazing dumpling recipe.
- Barbecue up some burgers and serve them with this classic potato salad recipe.
- Looking for an old fashioned dessert to go with your weeknight dinner? I highly recommend my mom’s rhubarb crisp recipe.
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Cheeseburger Casserole with Homemade Biscuit Topping
With simple ingredients like ground beef, cheese, ketchup, and biscuit topping, this quick & easy cheeseburger casserole is a weeknight dinner idea the whole family will love!
Ingredients
- 1 1/2 pounds ground beef
- Approximately 1 cup ketchup
- 1 1/2 cups grated cheddar cheese
- 3 cups flour
- 1 1/2 tablespoons baking powder
- 3 teaspoons sugar
- 3/4 teaspoons baking soda
- 1/4 teaspoon salt
- 3/4 cup butter
- 1 cup milk
Instructions
- Brown 1 1/2 pounds hamburger, seasoning with salt and pepper. Once cooked through, drain off fat and spoon into the bottom of a 9 x 13 inch pan. Squirt on a liberal amount of ketchup.
- Sprinkle on the grated cheese. (I’m sure any kind would do. We just happened to have cheddar.)
- Mix up the homemade biscuit dough. To make the homemade biscuits, stir together flour, baking powder, sugar, baking soda, and salt. Cut in the butter till mixture resembles course crumbs. Make a well in the center and add milk all at once. Stir just till dough clings together.
- On a lightly floured surface, knead the dough gently for 10-12 strokes. Roll to 1/2 inch thickness to the same size as the 9 x 13 inch pan. Place the rolled sheet of biscuit dough on top of the cheese layer of the casserole.
- Bake at 375 degrees until the biscuit layer is golden brown and cooked through - about 30-35 minutes.
Nutrition Information:
Yield: 8 Serving Size: 1Amount Per Serving: Calories: 693Total Fat: 40gSaturated Fat: 21gTrans Fat: 2gUnsaturated Fat: 15gCholesterol: 145mgSodium: 1098mgCarbohydrates: 48gFiber: 1gSugar: 10gProtein: 34g
This recipe was excellent! I combined it with some chopped green bell peppers. AMAZING!
This recipe was great! I added some diced green bell peppers with it. FANTASTIC!!
I remember loving this in the Wibaux school cafeteria, too! It brings back memories just reading about it. Thank you for sharing.